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  • Bioresearch Online: Virtual community for the bioresearch and life sciences industry featuring daily news, product updates, discussion forums, and online chat with information on manufacturing, technology, equipment, supplies, software, and careers.
  • BIOSCI - Bionet Electronic Newsgroup: Promotes communication between professionals in the biological sciences. Includes related resource links. From Stanford University.


     from Wikipedia

    Biology

    From Wikipedia, the free encyclopedia

    Jump to: navigation, search
    Escherichia coli Tree fern
    Goliath beetle Gazelle
    Biology studies the variety of life (clockwise from top-left) E. coli, tree fern, gazelle, Goliath beetle

    Biology (from Greek: ß???, bio, "life"; and ?????, logos, "knowledge") is the study of life. It is concerned with such topics as classifying the various forms of organisms, how species come into existence, and the interactions they have with each other and with the natural environment. Biology encompasses a broad spectrum of academic fields that are often viewed as independent disciplines. However, together they address phenomena related to living organisms (biological phenomena) over a wide range of scales, from biophysics to ecology.

    Many of the sub-disciplines of biology are ancient, such as botany, zoology, and medicine. However, biology as a unified science was first developed in the nineteenth century, as scientists discovered that all living things shared certain fundamental characteristics and were best studied as a whole. Today biology is one of the most prominent scientific fields. Over a million papers are published annually in a wide array of biology and medicine journals,[1] and biology is a standard subject of instruction at schools and universities around the world.

    As such a vast field, biology is divided into a number of subdisciplines. The old divisions by type of organism remains with subjects such as botany encompassing the study of plants, zoology with the study of animals, and microbiology as the study of microorganisms. The field may also be divided based on the scale at which it is studied: molecular biology looks at the fundamental chemistry of life; cellular biology looks a the basic building block of all life, the cell; Physiology looks at the internal structure of organism; and ecology looks at how various organisms interrelate. Applied fields of biology such as medicine are more complex and involve many specialized sub-disciplines.

    Principles

    Biology is a branch of science employing the scientific method to characterize and investigate knowledge. Scientific theories are based on scientific observations, and these theories are sometimes refined as new scientific information is compiled. Scientific theories can also be used to predict phenomena that has not yet been observed. Biological systems are sometimes statistically modeled, but as in other branches of science, theories are not always described using mathematics.

    The biological sciences are characterized and unified by several major underlying principles and concepts: universality, evolution, diversity, continuity, genetics, homeostasis, and interactions.

    However, biology is subject to the same physical laws that other branches of science obey, such as the laws of thermodynamics and conservation of mass.

    Universality

    Schematic representation of DNA, the primary genetic material.
    Schematic representation of DNA, the primary genetic material.
    Main article: Life

    While organisms may vary immensely in appearance, habitat, and behaviour it is a central principle of biology that all life shares certain universal fundamentals. A key feature is reproduction or replication. The entity being replicated, the replicator, in the past was considered to be the organism during the time of Darwin, but since the 1970s increasingly reduced to the scale of molecules.[2] All known life has a carbon-based biochemistry, carbon is the fundamental building block of the molecules that make up all known living things. Similarly water is the basic solvent for all known living organisms. While all these things are true of all organisms observed on Earth, in theory alternative forms of life could exist and some scientists do look at alternative biochemistry.

    All terrestrial organisms use DNA and RNA-based genetic mechanisms to hold genetic information. Another universal principle is that all observed organisms with the exception of viruses are made of cells. Similarly, all organisms share common developmental processes.

    Evolution

    Main article: Evolution

    A central organizing concept in biology is that all life has a common origin and has changed and developed through the process of the theory of evolution (see Common descent). This has led to the striking similarity of units and processes discussed in the previous section. Charles Darwin established evolution as a viable theory by articulating its driving force, natural selection (Alfred Russel Wallace is recognized as the co-discoverer of this concept). Darwin theorized that species and breeds developed through the processes of natural selection as well as artificial selection or selective breeding.Genetic drift was embraced as an additional mechanism of evolutionary development in the modern synthesis of the theory.

    The evolutionary history of a species— which describes the characteristics of the various species from which it descended— together with its genealogical relationship to every other species is called its phylogeny. Widely varied approaches to biology generate information about phylogeny. These include the comparisons of DNA sequences conducted within molecular biology or genomics, and comparisons of fossils or other records of ancient organisms in paleontology. Biologists organize and analyze evolutionary relationships through various methods, including phylogenetics, phenetics, and cladistics (The major events in the evolution of life, as biologists currently understand them, are summarized on this evolutionary timeline).

    Ever since its articulation by Darwin and Wallace, the theory of evolution by natural selection has come under attack by people who disagree with scientific findings or interpretations regarding the origins and diversity of life, generally favoring instead religious explanations. See Creation-evolution controversy for more information.

    Diversity

    A phylogenetic tree of all living things, based on rRNA gene data, showing the separation of the three domains bacteria, archaea, and eukaryotes as described initially by Carl Woese. Trees constructed with other genes are generally similar, although they may place some early-branching groups very differently, presumably owing to rapid rRNA evolution. The exact relationships of the three domains are still being debated.
    A phylogenetic tree of all living things, based on rRNA gene data, showing the separation of the three domains bacteria, archaea, and eukaryotes as described initially by Carl Woese. Trees constructed with other genes are generally similar, although they may place some early-branching groups very differently, presumably owing to rapid rRNA evolution. The exact relationships of the three domains are still being debated.

    Classification is the province of the disciplines of systematics and taxonomy. Taxonomy places organisms in groups called taxa, while systematics seeks to define their relationships with each other. This classification technique has evolved to reflect advances in cladistics and genetics, shifting the focus from physical similarities and shared characteristics to phylogenetics.

    Traditionally, living things have been divided into five kingdoms:

    Monera -- Protista -- Fungi -- Plantae -- Animalia

    However, many scientists now consider this five-kingdom system to be outdated. Modern alternative classification systems generally begin with the three-domain system:[3]

    Archaea (originally Archaebacteria) -- Bacteria (originally Eubacteria) -- Eukaryota

    These domains reflect whether the cells have nuclei or not, as well as differences in the cell exteriors.

    Further, each kingdom is broken down continuously until each species is separately classified. The order is:

    1. Kingdom
    2. Phylum
    3. Class
    4. Order
    5. Family
    6. Genus
    7. Species

    The scientific name of an organism is obtained from its genus and species. For example, humans would be listed as Homo sapiens. Homo would be the genus and sapiens is the species. Whenever writing the scientific name of an organism, it is proper to capitalize the first letter in the genus and put all of the species in lowercase; in addition the entire term would be put in italics or underlined. The term used for classification is called taxonomy.

    There is also a series of intracellular parasites that are progressively "less alive" in terms of metabolic activity:

    Viruses -- Viroids -- Prions

    Continuity

    Up into the 19th century, it was commonly believed that life forms could appear spontaneously under certain conditions (see abiogenesis). This misconception was challenged by William Harvey's diction that "all life [is] from [an] egg" (from the Latin "Omne vivum ex ovo"), a foundational concept of modern biology. It simply means that there is an unbroken continuity of life from its initial origin to the present time.

    A group of organisms shares a common descent if they share a common ancestor. All organisms on the Earth have been and are descended from a common ancestor or an ancestral gene pool. This last universal common ancestor of all organisms is believed to have appeared about 3.5 billion years ago. Biologists generally regard the universality of the genetic code as definitive evidence in favor of the theory of universal common descent (UCD) for all bacteria, archaea, and eukaryotes (see: origin of life).

    Homeostasis

    Main article: Homeostasis

    Homeostasis is the ability of an open system to regulate its internal environment to maintain a stable condition by means of multiple dynamic equilibrium adjustments controlled by interrelated regulation mechanisms. All living organisms, whether unicellular or multicellular, exhibit homeostasis. Homeostasis manifests itself at the cellular level through the maintenance of a stable internal acidity (pH); at the organismic level, warm-blooded animals maintain a constant internal body temperature; and at the level of the ecosystem, as when atmospheric carbon dioxide levels rise and plants are theoretically able to grow healthier and remove more of the gas from the atmosphere. Tissues and organs can also maintain homeostasis.

    Interactions

    Mutualistic symbiosis between clownfish of the genus Amphiprion that dwell among the tentacles of tropical sea anemones. The territorial fish protects the anemone from anemone-eating fish, and in turn the stinging tentacles of the anemone protects the clown fish from its predators.
    Mutualistic symbiosis between clownfish of the genus Amphiprion that dwell among the tentacles of tropical sea anemones. The territorial fish protects the anemone from anemone-eating fish, and in turn the stinging tentacles of the anemone protects the clown fish from its predators.

    Every living thing interacts with other organisms and its environment. One reason that biological systems can be difficult to study is that so many different interactions with other organisms and the environment are possible, even on the smallest of scales. A microscopic bacterium responding to a local sugar gradient is responding to its environment as much as a lion is responding to its environment when it searches for food in the African savannah. For any given species, behaviors can be co-operative, aggressive, parasitic or symbiotic. Matters become more complex when two or more different species interact in an ecosystem. Studies of this type are the province of ecology.

    Scope

    Biology has become such a vast research enterprise that it is not generally regarded as a single discipline, but a number do assist in understanding the genetic variation of a population; and physiology borrows extensively from cell biology in describing the function of organ systems. Ethology and comparative psychology extend biology to the analysis of animal behavior and mental characteristics, whilst Evolutionary psychology proposes that the field of psychology, including in regard to humans, is a branch of biology.

    Structure of life

    Schematic of typical animal cell depicting the various organelles and structures.
    Schematic of typical animal cell depicting the various organelles and structures.

    Molecular biology is the study of biology at a molecular level. This field overlaps with other areas of biology, particularly with genetics and biochemistry. Molecular biology chiefly concerns itself with understanding the interactions between the various systems of a cell, including the interrelationship of DNA, RNA, and protein synthesis and learning how these interactions are regulated.

    Cell biology studies the physiological properties of cells, as well as their behaviors, interactions, and environment. This is done both on a microscopic and molecular level. Cell biology researches both single-celled organisms like bacteria and specialized cells in multicellular organisms like humans.

    Understanding cell composition and how they function is fundamental to all of the biological sciences. Appreciating the similarities and differences between cell types is particularly important in the fields of cell and molecular biology. These fundamental similarities and differences provide a unifying theme, allowing the principles learned from studying one cell type to be extrapolated and generalized to other cell types.

    Genetics is the science of genes, heredity, and the variation of organisms. In modern research, genetics provides important tools in the investigation of the function of a particular gene, or the analysis of genetic interactions. Within organisms, genetic information generally is carried in chromosomes, where it is represented in the chemical structure of particular DNA molecules.

    Genes encode the information necessary for synthesizing proteins, which in turn play a large role in influencing (though, in many instances, not completely determining) the final phenotype of the organism.

    Developmental biology studies the process by which organisms grow and develop. Originating in embryology, modern developmental biology studies the genetic control of cell growth, differentiation, and "morphogenesis," which is the process that gives rise to tissues,